DOSE CONVERSIONS from other opioids should be done carefully and with close monitoring because of substantial affected individual variability in opioid analgesic response; seek advice from dose adjustment section for tips.Healthcare vendors are strongly encouraged to: finish a REMS-compliant education application, counsel people and/or their caregi
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Monitor for indicators and indications of withdrawal; when they arise, elevate the dose on the previous amount and taper a lot more little by little.Also, discontinuation of a concomitantly applied cytochrome P450 3A4 inducer may possibly cause an increase in oxycodone plasma concentration.Overdosage of oxycodone or interactions with other medicine
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